

🐠 Protect, Heal, Thrive — Because Your Fish Deserve the Best!
Seachem StressGuard is a premium slime coat protector designed to reduce stress and ammonia toxicity in fish during handling and transport. Its unique protein-binding colloidal agent promotes rapid healing of wounds and prevents infections without altering aquarium pH, making it safe for all aquatic environments including reefs and planted tanks. Trusted by hobbyists for over 30 years, StressGuard supports healthier, more resilient fish with flexible dosing tailored to your aquarium’s needs.
| ASIN | B005XOWNJE |
| ASIN | B005XOWNJE |
| Age Range Description | All Life Stages |
| Best Sellers Rank | #15,343 in Pet Supplies ( See Top 100 in Pet Supplies ) #130 in Aquarium Water Treatments |
| Brand Name | Seachem |
| Color | White |
| Customer Reviews | 4.8 4.8 out of 5 stars (1,568) |
| Date First Available | December 31, 1985 |
| Date First Available | December 31, 1985 |
| Directions | Use 1/2–1 capful (2.5–5 mL) to every 40 L (10 US gallons) daily until signs of stress have abated or healing is complete. Dose may be safely doubled. |
| Item Dimensions LxWxH | 4.5 x 6.88 x 11.5 inches |
| Item Package Dimensions L x W x H | 12.4 x 6.61 x 6.3 inches |
| Item Weight | 1 Kilograms |
| Item model number | 529 |
| Item model number | 529 |
| Manufacturer | Seachem Laboratories, Inc. |
| Manufacturer | Seachem Laboratories, Inc. |
| Model Name | StressGuard 4L |
| Product Dimensions | 4.5 x 6.88 x 11.5 inches; 2.2 Pounds |
| Size | 4 L |
| Specific Uses for Product | habitat |
| Style | Protection |
| Target Audience Keyword | fish, fish;algae-eaters; betta-fish; bottom-feeder-fish; cichlid-fish; goldfish; invertebrate-fish; mollusks; octopuses; rays; sharks; snails |
A**A
Must have!!!
This stuff is always great to have on hand, blue in color, no smell and doesn’t do much for water clarity as it is solely for aiding fish healing and health, definitely acts as a medication and works great for even fish with dropsy. We had rescued a dropsy fish from PetSmart and he had severe spinal curvature, we put him in a hospital tank to live the rest of his life happy, and he lasted almost an entire year!!!
T**R
Saved the day!
Stocking a 1,000-gallon freshwater community tank is no joke—for me or the fish. To help kickstart the cycle and establish good bacteria, I added 120 Longfin Congo Tetras and 550 Neon Tetras. But by day two, I noticed some of the Congos were showing signs of fin rot—tail fins disappearing fast. Not good. Turns out the stress of the move weakened their immune systems, making them vulnerable to the bacteria that cause this disease. I quickly realized that netting affected fish in a 13-foot-long aquarium just wasn’t going to happen, so I started looking for a broad-spectrum solution. That’s when I found Seachem StressGuard and decided to give it a try. I started treatment the very next day. I still lost a few fish—about 3 or 4—but they were already in pretty rough shape, with almost no tail fin left. The good news? The rest of the tank stabilized quickly, and I started seeing signs of healing and regrowth across the board. I used StressGuard for a full week—double-dosed the first three days, then tapered off for the next four. It wasn’t cheap, but it absolutely saved me from a much bigger loss. The fish bounced back, the disease stopped spreading, and the tank finally got a chance to settle and cycle properly. I've already picked up two more gallons of StressGuard for future use. From now on, I’ll be using it prophylactically every time I stock new fish. Discus are next—wish me luck! Huge thanks to Seachem—this product seriously saved the day!
H**R
My Axolotls love Stress Guard
Great product for Axolotls! My Axolotls are very healthy and this keeps their slime coat healthy. Great value for the money and the water stays clean and clear.
B**R
Hard Lesson Learned!
Fantastic product but if you’re transporting fish and you decide to use Stress Guard be VERY careful with your dosing! I learned the hard way.
K**G
Works Like Magic for Stubborn Betta Fin Rot
My betta and I have been fighting fin rot on and off for a while now. Recently figured out what the cause for the tears that allowed fin rot was, and removed it from the tank. I've tried lots of things, from aquarium salt to tablet based anti-fungal/bacterial medicines, which have all worked mildly for him. He was as happy and energetic as could be, but it was sad to see his fins torn and short all the time. I did some research, and I decided to try this Stressguard. My thought process was this: combine aquarium salt and Stressguard. The salt helped disinfect any open wounds, and the Stressguard would come in, bind to the exposed proteins in the wounds, promote regenration, and create a strong slime coat to protect against any foreign bodies. It worked perfectly! This combination, plus a 50% water change every day for a week straight allowed my betta to consistently regrow his fins back more than I had ever seen before. This product is awesome. You just mix in the appropriate dosage for your tank, and done. You can safely double the dosage, and you can add this to the water every day until your fish shows signs of improvement, as the bottle says. Not only does it help with healing and regrowth, but it helps with the stress of new water/water changes every day during treatment, and he was just chilling out like his normal self would and showed no signs of stress. The only downside to this product is that it does turn your water slightly blue and can stain, as it's a dark blue color, but that's no reason for you to not use it. I highly recommend trying this for stubborn fin rot. Protecting your fish's slime coat when treating fin rot is so widely overlooked, but I found it to be extremely effective.
W**D
Great Water Conditioner—Just Watch for Staining
I’ve been using this aquarium stress coat for a few weeks now and the results are impressive. It instantly calms my fish during water changes, and I’ve noticed less visible stress in the tank. It also helps with fin repair and removes chlorine/chloramine effectively. One word of caution—the blue dye in this product does stain, so be extra careful when pouring or measuring. A few drops on your hands or countertop will leave a mark if not wiped up immediately. Despite that, it’s a solid product and does exactly what it claims. I recommend using a dedicated measuring cup or syringe and handling over a sink. A great addition to any aquarium care routine!
R**S
Love this product!
I have rainbow fish that are susceptible to getting fungal infections, and I use Seachem Stress Guard double strength when the fish show initial signs of getting a fungal infection, and it miraculously cures them almost every time!!
L**R
Aquarium must have
Awesome addition to your aquarium needs
K**M
Amazing stuff was not too sure at first if it would harm my fish as I read a bunch of different comments. my one disc hurt it’s Finn and I noticed it was kind of looking like it was torn and rotten ,so I put this stuff in my 55 gallon aquarium five cap fulls daily for six days and after day two his been look so much better And today on day 6 you can’t even tell he was injured. It actually calmed the other fish down and they didn’t pick on him definitely recommend doesn’t make your water cloudy or affect life plants. As you can see the blue guy is back to normal and enjoying life with his buddies again
C**A
Ok
V**I
Better deal ..bought it
S**N
It helps and you can actually see ur fishes more happy would suggest everyone to buy, those who have an aquarium I ment
T**G
Does what it says and is easy to use.Functional and good value for money.
Trustpilot
1 week ago
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