No they cannot. They are not supposed to dissolve in your stomach which is why they are to be taken on an empty stomach to have any effect. If you cut them, it affects the coating on the pill. They do come in different doses however so hopefully you can find one that suits your needs.

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NOW Supplements, SAMe (S-Adenosyl-L-Methionine) 400 mg, Nervous System Support*, 60 Tablets

NOW Supplements, SAMe (S-Adenosyl-L-Methionine) 400 mg, Nervous System Support*, 60 Tablets

Q: I thought Sam-E needed to be in blister packs to preserve the pills themselves. I notice these are not. Is there a reason why?

The blister pack is one issue - I notice they recommend refrigerating these after opening which would help preserve.The more important point to me is that these have no mannitol (stomach upsetting) in themand that they are a true 400mg dose of SAM-e- not 400mg of the salt compound as many others are.

Q: What size are these pills? I have a hard time swallowing pills.

Long flat tablets, 7/8” X 3/8”, smooth coating, I find them easy to swallow. Don’t break them, they are enteric coated. Exposure to your stomach acids will significantly impact their effectiveness.

Q: Where where they made? good practices facility does not mean anything to me. they packed them in usa but where were they made? what country?

At NOW, our products are manufactured in the U.S. In regards to sourcing, our raw material sourcing is subject to change, so please contact us directly for information like country of origin. Anything we post here will later be inaccurate whenever we do make a change, so we are hesitant to post temporarily accurate information in a permanently accessible public forum. Our certified nutritionists can be reached at 888-669-3663 ext. 5 or productinfo@nowfoods.com.

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Product ID: 276580624

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Details

Brand
NOW
Flavour
Unflavored
Primary supplement type
Unit count
60.00 Count
Item form
Tablet
Item weight
91 g

🌱Vegan & allergen-free

💊400 mg potent dose

🛡️Enteric-coated for max absorption

Description

💡 Elevate your mood and mobility—because your brain and joints deserve the best!

FLEXIBLE DOSING - Take 1 tablet 2-4 times daily to tailor support to your lifestyle and needs.
TRUSTED HERITAGE - Crafted by a family-owned USA company since 1968, blending tradition with quality.
CLEAN PURE FORMULA - Free from dairy, eggs, gluten, soy, and sugar—perfect for mindful wellness seekers.
OPTIMIZED ABSORPTION - Enteric-coated tablets protect SAMe from stomach acid, ensuring effective delivery.
BRAIN JOINT SYNERGY - Supports neurotransmitter synthesis and joint comfort for active minds and bodies.

NOW Supplements SAMe delivers a clinically supported 400 mg dose of S-adenosylmethionine in enteric-coated tablets, enhancing brain biochemistry and joint health. This vegan, allergen-free formula is crafted in the USA by a trusted family-owned brand, designed for superior absorption and flexible daily use.

Have a Question? See What Others Asked

I thought Sam-E needed to be in blister packs to preserve the pills themselves. I notice these are not. Is there a reason why?

What size are these pills? I have a hard time swallowing pills.

Can these be cut?

Where where they made? good practices facility does not mean anything to me. they packed them in usa but where were they made? what country?

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TrustScore 4.5 | 7,300+ reviews

Neha S.

Excellent communication throughout the order process. Product is perfect.

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Additives	Sugar
Allergen Information	Egg Free, Dairy Free, Soy Free
Weight	0.24 Kilograms
Units	60.00 Count
Serving Recommendation	1 Tablet
Brand	NOW
Format	Tablet
Age Range Description	Adult

NOW Supplements, SAMe (S-Adenosyl-L-Methionine) 400 mg, Nervous System Support*, 60 Tablets

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