

✨ Clear skin, confident you — the future-proof acne solution! 💼
Differin Acne Treatment Gel delivers a prescription-strength 0.1% Adapalene retinoid in a gentle, water-based formula designed for sensitive, acne-prone skin. With a 90-day supply, it works deep within pores to clear existing breakouts and prevent new ones, clinically reducing acne by up to 87% in 12 weeks. Oil-free and fragrance-free, it supports long-term skin clarity, texture restoration, and minimizes scarring risk, making it a trusted choice for professionals seeking effective, science-backed skincare.















| ASIN | B07ZTN5N1V |
| ASIN | B07ZTN5N1V |
| Customer reviews | 4.6 4.6 out of 5 stars (9,368) |
| Date First Available | 24 February 2020 |
| Department | Beauty & Personal Care |
| Department | Beauty & Personal Care |
| Item model number | 0299.491040 |
| Item model number | 0299.491040 |
| Manufacturer | Galderma |
| Manufacturer | Galderma |
| Product Dimensions | 4.29 x 7.11 x 17.78 cm; 45 g |
| Product Dimensions | 4.29 x 7.11 x 17.78 cm; 45 g |
J**.
Dried my skin
I used it only for 3 days and it dried my skin so much that I had red patches. Stopped using immediately
P**A
I’ve used Differin Gel on and off for years, and it’s consistently dependable in helping keep my skin clear and breakout-free. It’s gentle enough for sensitive, acne-prone skin yet effective in preventing clogged pores and future breakouts. I also like using it as part of my anti-aging routine. it’s a great alternative to tretinoin on days when I want something a little milder but still effective. The texture absorbs well without irritation or dryness when used correctly, and it layers nicely under moisturizer. For a 90-day supply, the price is absolutely worth it considering how well it maintains skin clarity and smoothness. Differin remains one of those reliable, science-backed products I always keep in my rotation for long-term skin health and maintenance.
S**H
I’ve been using Differin Acne Treatment Gel consistently, and it’s one of the most effective acne products I’ve tried, especially for long-term results. The 0.1% adapalene formula feels lightweight and spreads easily, and the pump packaging makes it simple to dispense the right amount without waste. What I appreciate most is how gentle it is compared to other retinoids. When I first started, I eased into it, and while there was some mild dryness, it was manageable and temporary. With regular use, my skin adjusted well, and I started noticing fewer breakouts and smoother texture overall. It doesn’t feel harsh or irritating when used properly, which is a big plus for sensitive or acne-prone skin. Over time, Differin has helped reduce clogged pores and the frequency of new breakouts. It’s not an overnight fix, but with patience and consistency, the results are real and noticeable. It layers well with moisturizer and doesn’t pill, making it easy to fit into a nighttime routine. Overall, this is a reliable, dermatologist-recommended acne treatment that delivers results without being overly aggressive. If you’re looking for a proven retinoid that works gradually and gently, Differin is a solid choice and well worth sticking with.
B**Y
I really like this for acne. I had to let my skin get used to Differin before I could use it every night. At first it really dried out my skin but I changed to only 1 time a week and changed to every other day and now it works out great! My Dermatologist suggested it for me and I found it on Amazon of course! Price was reasonable and I put it on my subscription which helps a lot. If you do have acne I definitely suggest you try this but only if you're over 12 yrs old. Also, use moisturizer with it.
S**L
I’ve struggled with persistent breakouts for years, and the Differin Acne Treatment Gel (90 Day Supply, 0.1% Adapalene) has honestly been a game changer for my skin. This retinoid treatment delivers real results without the harsh irritation I’ve experienced with so many other products. ✨ Cleared My Acne: After consistent use, my breakouts have significantly reduced. Even stubborn spots heal faster, and I’m seeing fewer new blemishes overall. 🧴 Gentle Yet Effective: I was worried a retinoid gel would dry out my skin, but this formula feels lightweight and absorbs quickly. I experienced minimal peeling or irritation—just steady improvement. 📆 Great Value: A 90‑day supply is generous and makes it easy to stay consistent, which is key with acne treatments. A little goes a long way, so the tube lasts! 💡 Easy to Use: I apply it once a day at night after cleansing, and it layers beautifully under moisturizer without pilling. If you’re serious about clearing acne and improving skin texture, Differin is worth trying. It’s hands‑down one of the most effective over‑the‑counter acne treatments I’ve used! 🌟🧖♀️💧
K**E
This gel has been effective for helping improve breakouts and overall skin texture. Like most retinoids, there was an adjustment period with some dryness and mild irritation at first, but that improved with consistent use and good moisturizing. If you’re new to retinoids, start slowly and ease into it. Overall, it works well once your skin adjusts.
Trustpilot
2 weeks ago
1 week ago