








🧬 Elevate your wellness game with the folate that champions trust!
Thorne 5-MTHF delivers 1mg of bioactive methylfolate per capsule, supporting healthy methylation, cardiovascular, and neurological function. Manufactured in the USA with allergen-free, pure ingredients, it’s trusted by over 100 professional sports teams and developed in partnership with the Mayo Clinic. Ideal for adults seeking superior folate absorption, especially those with MTHFR genetic variations.











| ASIN | B00FY8IQ7C |
| ASIN | B00FY8IQ7C |
| Amazon Bestseller | #73,117 in Health & Personal Care ( See Top 100 in Health & Personal Care ) #144 in Vitamin B9 (Folic Acid) Supplements |
| Country of Origin | USA |
| Customer Reviews | 4.7 4.7 out of 5 stars (3,661) |
| Date First Available | February 12, 2014 |
| Is Discontinued By Manufacturer | No |
| Item model number | B129 |
| Main Ingredients | 5-MTHF |
| Manufacturer | Thorne Research |
| Target Age Range Description | Adult |
| Target Gender | Unisex |
A**S
I started taking Thorne 5-MTHF after genetic testing revealed I have MTHFR mutations that affect my body's ability to process regular folic acid. My functional medicine doctor specifically recommended this Thorne product for its superior quality and bioavailable form of folate, and I've been consistently impressed with both the product quality and the health improvements I've experienced. What sets this supplement apart is the methylated form of folate, which bypasses the genetic conversion issues that affect many people. Within a few weeks of starting this supplement, I noticed improvements in my energy levels and overall sense of well-being that I hadn't experienced with regular B-vitamin complexes. My follow-up lab work showed significant improvement in my homocysteine levels, which was exactly what my doctor was hoping to achieve. The quality control and purity that Thorne is known for is evident in this product. The capsules are clean with no unnecessary fillers or artificial ingredients, and I've experienced no digestive upset or side effects. The dosing is appropriate and easy to incorporate into my daily supplement routine. The cardiovascular and neurological support benefits align perfectly with what my healthcare provider explained about methylfolate's role in cellular function. I feel confident knowing this is supporting my body's methylation processes that are crucial for so many aspects of health. The packaging protects the supplements well, and the expiration dates are always well into the future, indicating proper storage and handling. Highly recommend for anyone needing bioavailable folate, especially those with MTHFR mutations - excellent quality from a trusted brand that healthcare providers consistently recommend.
R**A
ok
R**A
This is the best product for me. But its bit costly . It worth it
S**R
great
C**A
I've been taking these for several months now, primarily because I have the MTHFR gene variation that makes it hard to process regular folic acid. Pros: -Bioavailability: Unlike synthetic folic acid, this is already in the methylated form, so my body can use it directly. I've noticed improved energy levels, better mood stability, and less of the "foggy" feeling I used to live with. -Purity & Quality: Thorne is known for third-party testing and minimal fillers, just cellulose capsule and the active ingredients. No gluten, dairy, or unnecessary additives. Perfect for people with sensitivities. -Supports Key Areas: It's great for methylation support, homocysteine regulation, nerve health, and overall cardiovascular wellness. -Easy to Take: Super small capsules, 60 per bottle (2-month supply at 1 per day), no taste or aftertaste. Cons (very minor): It's premium-priced compared to generic folic acid supplements, but you get what you pay for in terms of purity and effectiveness. If you're new to methylfolate, start slow, some people experience mild overstimulation at first (I didn't, but it's common advice). This has become a non-negotiable in my daily stack. If you need active B9 folate, Thorne's 5-MTHF is top-tier. Highly recommend! ⭐⭐⭐⭐⭐
Trustpilot
1 month ago
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